Brain Health
Ashwagandha promotes memory and cognition in two ways: by impacting cognitive function directly, and by lowering stress and improving sleep and mental alertness. KSM-66 Ashwagandha root extract has been clinically proven to improve executive function, immediate memory, information processing speed, and concentration.
Study 1
Title: A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly reduced stress and anxiety assessment scores and serum cortisol levels, compared to a placebo. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in enhancing stress resistance and improving quality of life.
Chandrasekhar et al., 2012; Indian journal of psychological medicine, 34(3), 255–262.Study 2
Title: Body Weight Management in Adults Under Chronic Stress Through Treatment with Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly reduced stress and food cravings scores and serum cortisol levels, compared to the placebo. Ashwagandha root extract also significantly increased happiness scores. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in reducing stress resistance and stress-related food cravings.
Choudhary D et al., 2017; Journal of evidence-based complementary & alternative medicine, 22(1), 96–106Study 3
Title: Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
Conclusion: The study demonstrated that Ashwagandha root extract (250mg/day and 600mg/day) significantly reduced stress, anxiety, and serum cortisol levels, compared to the placebo. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in reducing stress and anxiety (600mg/day being more efficacious, compared to 250mg/day).
Salve, J., et al (2019).Cureus, 11(12), e6466.Study 4
Title: Efficacy and Safety of Ashwagandha Root Extract in the Management of Frailty in Older Adults: A Prospective, Randomized, Placebo-Controlled Study
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly reduced frailty score, perceived stress score, serum cortisol level, and improved quality of life in elderly participants. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving stress resistance and overall well-being in the elderly.
Efficacy and Safety of Ashwagandha Root Extract in the Management of Frailty in Older Adults: A Prospective, Randomized, Placebo-Controlled Study (Under Peer Review).Study 5
Title: Adaptogenic and Immunomodulatory Activity of Ashwagandha Root Extract: An Experimental Study in an Equine Model.
Conclusion: The study demonstrated that Ashwagandha root extract supplementation (2.5 gm/animal, 5 gm/animal, and 10 gm/animal per day) in horses exhibited a significant reduction in cortisol and epinephrine levels and an increase in hemoglobin, total erythrocyte count, total leucocyte counts, and lymphocyte percentage.The findings suggest that Ashwagandha root extract is safe and effective in reducing stress in horses.
Priyanka G et al., 2020, Frontiers in Veterinary Sciences 7:541112.Study 6
Title: Efficacy and Safety of Standardized Ashwagandha (Withania somnifera) Root Extract on Reducing Stress and Anxiety in Domestic Dogs: A Randomized Controlled Trial.
Conclusion: The study demonstrated that Ashwagandha root extract supplementation (15 mg/kg body weight) in dogs significantly reduced cortisol levels, fear and anxiety, and CBPI pain severity and pain interference domain scores compared to placebo. The supplementation was well-tolerated with no adverse events reported. The findings suggest that Ashwagandha root extract is safe and effective in reducing stress, fear, and anxiety in dogs.
Kaur J, et al., (2022) Journal of Veterinary Behavior, 51, 8-15.Study 7
Title: Adaptogenic Ashwagandha root extract modulates inflammatory markers in feline stress management: a double-blind placebo-controlled clinical trial.
Conclusion: The study demonstrated that supplementation with Ashwagandha root extract (15 mg/kg body weight) in cats significantly reduced cortisol levels and increased hematological parameters. No detrimental changes were observed in liver and kidney function parameters. The supplementation was well-tolerated, with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in reducing stress and inflammation in cats.
Devarasetti, A. K., et al., (2024). Journal of Applied Animal Research, 52(1).Study 1
Title: Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved sleep actigraphy parameters such as sleep onset latency, total sleep time, and sleep efficiency, compared to the placebo. Ashwagandha root extract also significantly reduced anxiety. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in reducing anxiety and improving sleep in adults.
Langade, D., et al (2019). Cureus, 11(9), e5797Study 2
Title: Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly reduced anxiety and improved sleep actigraphy parameters such as sleep onset latency, total sleep time, sleep efficiency, and mental alertness on rising compared to the placebo in both healthy participants and insomnia patients. The supplementation was well-tolerated, and no adverse events were reported. These findings suggest that Ashwagandha root extract is safe and effective in reducing anxiety and improving sleep for both healthy participants and insomnia patients.
Langade, D., et al., (2020). Journal of Ethnopharmacology: 264:113276.Study 3
Title: Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
Conclusion: The study demonstrated that Ashwagandha root extract (250mg/day and 600mg/day) significantly improved the quality of sleep. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving sleep and reducing anxiety (600mg/day being more efficacious, compared to 250 mg/day).
Salve, J., et al (2019).Cureus, 11(12), e6466.Study 4
Title: Efficacy and Tolerability of Ashwagandha Root Extract in the Elderly for Improvement of General Well-being and Sleep: A Prospective, Randomized, Double-blind, Placebo-controlled Study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved sleep quality, quality of life, and mental alertness on rising in elderly participants. The supplementation was well-tolerated, and no adverse events were reported. These findings suggest that Ashwagandha root extract is safe and effective in improving sleep and general well-being in the elderly.
Kelgane, S. B., et al., (2020). Cureus, 12(2), e7083.Study 5
Title: Efficacy and Safety of Ashwagandha Root Extract in the Management of Frailty in Older Adults: A Prospective, Randomized, Placebo-Controlled Study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved sleep quality, quality of life, and cognitive function in elderly participants. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving sleep, cognitive function, and overall well-being in the elderly.
Efficacy and Safety of Ashwagandha Root Extract in the Management of Frailty in Older Adults: A Prospective, Randomized, Placebo-Controlled Study (Under Peer Review).Study 6
Title: A clinical assessment of the pharmacological effects of Ashwagandha root extract on parent-reported functions of cognition, behavior, sleep, fatigue, and executive function in children aged 6-12 years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly improved Sleep Disturbance Scale for Children scores, indicating better sleep-related behavior in children. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in enhancing children's sleep quality.
A clinical assessment of the pharmacological effects of Ashwagandha root extract on parent-reported functions of cognition, behavior, sleep, fatigue, and executive function in children aged 6-12 years (Under Peer Review).Study 7
Title: Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly reduced Hyperactivity-Impulsivity domain scores, sleep disturbance, and anxiety in children. KSM-66 Ashwagandha did not show any significant effect on the hepatic and renal parameters. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving sleep quality and symptoms of ADHD in children.
Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years (Under Peer Review).Study 1
Title: Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved immediate memory, general memory, executive function, and attention and information processing speed, compared to placebo in adults. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in enhancing memory, executive function, and attention in adults.
Choudhary, D., et al., (2017). Journal of dietary supplements, 14(6), 599–612.Study 2
Title: Ashwagandha Root Extract on Cognition, Energy, and Mood in Adults with Cognitive and Energy Problems: A Prospective, Placebo-Controlled Study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved episodic memory, working memory, executive function, and the accuracy of attention, mental fatigue, mood, and vigor, compared to a placebo in adults. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving memory, cognition, mood, and fatigue in adults.
Kale, S., et al., (2024), Journal of psychoactive drugs, 1–13.Study 3
Title: A clinical assessment of the pharmacological effects of Ashwagandha root extract on parent-reported functions of cognition, behavior, sleep, fatigue, and executive function in children aged 6-12 years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly improved episodic memory, working memory, attention, executive function, and information processing speed, compared to the placebo group. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in enhancing children's memory, cognition, and executive function.
A clinical assessment of the pharmacological effects of Ashwagandha root extract on parent-reported functions of cognition, behavior, sleep, fatigue, and executive function in children aged 6-12 years (Under Peer Review).Study 4
Title: Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly reduced Inattention and Hyperactivity-Impulsivity domain scores, and anxiety in children. KSM-66 Ashwagandha did not show any significant effect on the hepatic and renal parameters. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving attention, and symptoms of ADHD in children.
Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years (Under Peer Review)Sports Health
Ashwagandha enhances athletic performance by boosting muscle growth, strength, and endurance. It improves cardiovascular endurance by increasing VO2 max, which is crucial for athletes in stamina-demanding sports. KSM-66 Ashwagandha root extract is clinically proven to enhance physical performance by supporting muscle recovery and reducing the impact of stress on the body during intense physical activity.
Study 1 - Cardiorespiratory endurance (AYU)
Title: Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved maximal oxygen capacity and quality of life compared to a placebo in adults. The supplementation was well-tolerated, and no adverse events were reported. These findings suggest that Ashwagandha root extract is safe and effective in improving cardiorespiratory endurance and overall quality of life in adults.
Choudhary, B., et al. (2015). Ayu, 36(1), 63–68.Study 2 - Cardiorespiratory endurance and Recovery
Title: A double-blind, randomized, placebo-controlled trial on the effect of Ashwagandha (Withania somnifera dunal.) root extract in improving cardiorespiratory endurance and recovery in healthy athletic adults.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved maximal oxygen capacity and total quality recovery, compared to a placebo in adults. The supplementation was well-tolerated, and no adverse events were reported. These findings suggest that Ashwagandha root extract is safe and effective in improving cardiorespiratory endurance and overall quality of recovery in adults.
Tiwari, S., et al., (2021). Journal of ethnopharmacology, 272, 113929.Study 3 - Muscle Strength and Endurance (F1000)
Title: Effects of Ashwagandha (Withania somnifera) standardized root extract on physical endurance and VO2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved maximal oxygen capacity and strength in both men and women. The supplementation was well-tolerated, and no adverse events were reported. These findings suggest that Ashwagandha root extract is safe and effective in improving muscle strength and endurance in healthy adults.
Verma N, et al., (2023), F1000Research 2023, 12:335.Study 1 - Muscle strength, recovery and testosterone
Title: Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved muscle strength, muscle size and serum testosterone levels. There was a reduction in serum creatine kinase levels indicating faster recovery. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving muscle strength and testosterone levels, and recovery in adults.
Wankhede, S., et al., (2015).Journal of the International Society of Sports Nutrition, 12, 43.Study 2 - Muscle Strength and Endurance (F1000)
Title: Effects of Ashwagandha (Withania somnifera) standardized root extract on physical endurance and VO2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved muscle strength, muscle size for arm, thigh and chest and cardiorespiratory endurance in both men and women. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving muscle strength and endurance in healthy adults.
Verma N, et al., (2023), F1000Research 2023, 12:335.Study 3 - Muscle Recovery and Testosterone
Title: Effect of Ashwagandha Root Extract on Serum Testosterone and Muscle Recovery in Strength Training.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly reduced the serum creatinine phosphokinase levels indicating faster recovery in both men and women. In addition, it significantly improved free testosterone and total testosterone levels in men. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in faster recovery in both men and women.
Verma N, et al., (2023), IJMPR, 4(5):371-381.Study 1 - Muscle strength and recovery
Title: Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved serum testosterone levels. In addition there was a significant increase in muscle strength and muscle while a significant reduction in serum creatine kinase levels indicating faster recovery. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving testosterone levels, muscle strength and recovery in adults.
Wankhede, S., et al., (2015).Journal of the International Society of Sports Nutrition, 12, 43.Study 2 - Muscle Recovery and Testosterone
Title: Effect of Ashwagandha Root Extract on Serum Testosterone and Muscle Recovery in Strength Training.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved free testosterone and total testosterone levels in men. There was a reduction in serum creatinine phosphokinase levels indicating faster recovery. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving testosterone levels and recovery in men.
Verma N, et al., (2023), IJMPR, 4(5):371-381.Children's Health
Ashwagandha plays a crucial role in kids' wellness as a nootropic and adaptogen for calmness, sleep, focus, and cognition. KSM-66 Ashwagandha root extract is clinically proven to improve sleep, behaviour and emotional regulation, memory, concentration and focus in children.
Study 1
Title: Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly reduced Inattention and Hyperactivity-Impulsivity domain scores, sleep disturbance, and anxiety in children. KSM-66 Ashwagandha did not show any significant effect on the hepatic and renal parameters. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving attention, sleep quality and symptoms of ADHD in children.
Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years (Under Peer Review).Study 1
Title: A clinical assessment of the pharmacological effects of Ashwagandha root extract on parent-reported functions of cognition, behavior, sleep, fatigue, and executive function in children aged 6-12 years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly improved episodic memory, working memory, attention, executive function, and information processing speed, compared to the placebo group. Additionally, improved Sleep Disturbance Scale for Children scores, indicating better sleep-related behavior in children. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in enhancing children's memory, cognition, and sleep quality.
A clinical assessment of the pharmacological effects of Ashwagandha root extract on parent-reported functions of cognition, behavior, sleep, fatigue, and executive function in children aged 6-12 years (Under Peer Review).Study 2
Title: Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly reduced Inattention and Hyperactivity-Impulsivity domain scores, sleep disturbance, and anxiety in children. KSM-66 Ashwagandha did not show any significant effect on the hepatic and renal parameters. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving attention, sleep quality, and symptoms of ADHD in children.
Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years (Under Peer Review).Study 1
Title: A clinical assessment of the pharmacological effects of Ashwagandha root extract on parent-reported functions of cognition, behavior, sleep, fatigue, and executive function in children aged 6-12 years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly improved episodic memory, working memory, attention, executive function and information processing speed, compared to the placebo group. Additionally, improved Sleep Disturbance Scale for Children scores, indicating better sleep-related behavior in children. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in enhancing children's memory, cognition, and sleep quality.
A clinical assessment of the pharmacological effects of Ashwagandha root extract on parent-reported functions of cognition, behavior, sleep, fatigue, and executive function in children aged 6-12 years (Under Peer Review).Study 2
Title: Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years.
Conclusion: The study demonstrated that Ashwagandha root extract (300mg/day) significantly reduced Inattention and Hyperactivity-Impulsivity domain scores, sleep disturbance, and anxiety in children. KSM-66 Ashwagandha did not show any significant effect on the hepatic and renal parameters. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving attention, sleep quality and symptoms of ADHD in children.
Efficacy of Ashwagandha Root Extract in Treatment of Hyperactivity Disorder (ADHD) in Children Aged 5-12 Years (Under Peer Review).Study 1 - Male Fertility and Testosterone
Title: Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study.
Conclusion: The study demonstrated that Ashwagandha root extract (mg/day) significantly improved sperm concentration, semen volume, sperm motility, and serum testosterone levels. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving male fertility and testosterone levels.
Ambiye, V. R., et al., (2013). Evidence-based complementary and alternative medicine : eCAM, 2013, 571420.Study 2 - Sexual Wellness in Men
Title: Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved sexual functions, arousal, orgasm, and sexual drive.There was also a significant increase in physical functioning, energy/fatigue, emotional well-being, social functioning, pain and general well-being. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving sexual wellness in men.
Chauhan, S., et al., (2022). Health science reports, 5(4), e741.Study 3 - Male Fertility, Sexual Wellness and Testosterone in Men
Title: Efficacy and Safety of Eight-Week Therapy with Ashwagandha Root Extract in Improvement of Sexual Health in Healthy Men: Findings of a Prospective, Randomized, Double-Blind, Placebo-Controlled Study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved serum testosterone and dihydrotestosterone levels. There was also a significant improvement in semen volume, sperm count and sperm motility. In addition there was a significant increase in the level of sexual desire scores, number of satisfying sexual events, International Index of Erectile Function scores and improvement in overall quality of life. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving sexual wellness in men.
Efficacy and Safety of Eight-Week Therapy with Ashwagandha Root Extract in Improvement of Sexual Health in Healthy Men: Findings of a Prospective, Randomized, Double-Blind, Placebo-Controlled Study (Accepted for Publication).Study 4 - Sexual Wellness and Testosterone in Men
Title: Ashwagandha Root Extract Improves Sexual Health in Healthy Men: Findings of a Prospective, Randomized, Double-Blind, Placebo-Controlled Study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved total and free testosterone, sperm concentration, semen volume, sperm volume, level of sexual desire. There was also a significant increase in erectile function and quality of life. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving sexual wellness and testosterone in men.
Ashwagandha Root Extract Improves Sexual Health in Healthy Men: Findings of a Prospective, Randomized, Double-Blind, Placebo-Controlled Study (Under Peer Review).Study 5 - Sexual Wellness in Men (USA)
Title: Role of Ashwagandha Extract in Improving Sexual Health in Healthy Men: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study.
Conclusion: The study demonstrated that Ashwagandha root extract (600mg/day) significantly improved serum testosterone levels, level of sexual desire and Number of Satisfying Sexual Event scores. The supplementation was well-tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving sexual wellness and testosterone in men.
Role of Ashwagandha Extract in Improving Sexual Health in Healthy Men: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study (Under Peer review).Study 1 - Sexual Health in Women
Title: Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study.
Conclusion: The study showed that arousal, desire, orgasm, lubrication, and satisfaction domains as well as overall female sexual function index scores significantly improved with ashwagandha root extract (600 mg/day). A significant decrease in female sexual distress scale scores and an increase in the number of successful sexual encounters are also observed. The supplementation was well tolerated with no adverse events reported. These findings suggest that Ashwagandha root extract is safe and effective in improving sexual wellness in women.
Dongre, S. et al., 2015. BioMed Research International, 2015, 284154.Study 2 - Sexual Wellness and General Well-being in Women
Title: Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for Improvement of Sexual Health in Healthy Women: A Prospective, Randomized, Placebo-Controlled Study.
Conclusion: The study demonstrated a significant improvement in arousal, desire, orgasm, lubrication, and satisfaction domains, as well as overall female sexual function index scores with ashwagandha root extract (600 mg/day). A significant decrease in female sexual distress scale scores and an increase in the number of successful sexual encounters and overall quality of life are also observed. The supplementation was well-tolerated, with only mild adverse effects comparable to the placebo group and no serious adverse events. These findings suggest that Ashwagandha root extract is safe and effective in improving sexual wellness in women.
Ajgaonkar A, et al., (2022) Cureus 14(10): e30787.Study 3 - Sexual Well-being in Women
Title: Efficacy and safety of ashwagandha root extract on sexual health in healthy women: findings of a prospective, randomized, double-blind, placebo-controlled study.
Conclusion: The study demonstrated a significant improvement in overall female sexual function index scores as well as arousal, desire, orgasm, lubrication, and satisfaction domains with ashwagandha root extract (600 mg/day). A significant improvement in the number of successful encounters and the level of sexual desire is observed. A significant reduction in the female sexual distress scale and perceived stress scores are also observed. The supplementation also resulted in an increase in estrogen levels and a reduction in follicle-stimulating hormone levels.
Mutha A, et al., (2025) Cogent Psychology, 12:1, 2459467Study 4 - Sexual Wellness in Women
Title: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Effects of KSM-66 Ashwagandha® capsule (300 mg) on Sexual Health in Healthy Women.
Conclusion: The study demonstrated a significant improvement in overall female sexual function index scores as well as arousal, desire, orgasm, lubrication, and satisfaction domains with ashwagandha root extract (600 mg/day). A significant improvement in the number of intercourses, satisfying sexual activity and the level of sexual desire is observed. A significant reduction in the female sexual distress scale and perceived stress scores are also observed. The supplementation also resulted in an increase in estrogen levels and a reduction in progesterone hormone levels.
A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Effects of KSM-66 Ashwagandha® capsule (300 mg) on Sexual Health in Healthy Women (Accepted for Publication).Study 5 - Sexual Wellness in Women
Title: Effects of Ashwagandha Extract (Capsule KSM-66 300 mg) on Sexual Health in Healthy Women: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study.
Conclusion: The study demonstrated a significant improvement in overall female sexual function index scores as well as arousal, desire, orgasm, lubrication, and satisfaction domains with ashwagandha root extract (600 mg/day). A significant improvement in the number of intercourses, number of orgasms, and the level of sexual desire is observed. A significant reduction in the female sexual distress scale and perceived stress scores are also observed. The supplementation also resulted in an increase in estrogen levels.
Effects of Ashwagandha Extract (Capsule KSM-66 300 mg) on Sexual Health in Healthy Women: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study (Under Peer Review)